THE 2-MINUTE RULE FOR GR

Only one nucleotide polymorphism that replaces A with G at the nucleoside 3669 (A3669G) situated in the 3’ stop of exon 9b is explained in a eu inhabitants (461). This polymorphism would not change the amino acid sequence but boosts the balance of GRb mRNA and boosts GRb protein expression, bringing about higher inhibition of GRa-induced transcri